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“PHYSIOLOGICAL AND MOLECULAR GENETIC EFFECTS OF TIME-VARYING ELECTROMAGNETIC FIELDS ON HUMAN NEURONAL CELLS” (SEPTEMBER 2003) (NASA/TP-2003-212054)

NASA 4-year collaborative study on the efficacy of electromagnetic fields to stimulate growth and repair in mammalian tissues NASA/TP-2003-212054*


http://ston.jsc.nasa.gov/collections/TRS/_techrep/TP-2003-212054.pdf


CHIEF INVESTIGATORS:
Robert Dennis, PhD - University of Michigan, Ann Arbor, MI, USA
Thomas J. Goodwin, PhD - NASA Johnson Space Center (JSC), Houston, TX, USA

 

PURPOSE
This four-year study used human donors to “define the most effective electromagnetic fields for enhancing growth and repair in mammalian tissues.”

The study wanted to utilize “nerve tissue which has been refractory to efforts to stimulate growth or enhance its repair regardless of the energy used.” (All other tissues have demonstrated growth and repair stimulation with appropriate PEMF.)

In addition, the study attempted to define a PEMF technology that would “duplicate mature, three-dimensional morphology between neuronal cells and feeder (glial) cells, which has not been previously accomplished.”

 

STUDY RESULTS
The PEMF used in the study “caused accelerated growth rate and better organized morphology over controls” and resulted in “greater cell viability” (85% vs. 65%). In the gene discovery array (chip technology that surveyed 10,000 human genes), the investigators found up-regulation of 150 genes associated with growth and cell restoration.

NASA’S RECOMMENDATIONS

“One may use square wave EM fields with rapid rate of change" for:

 

  • REPAIRING TRAUMATIZED TISSUES

  • MODERATING SOME NEURODEGENERATIVE DISEASES

  • DEVELOPING TISSUES FOR TRANSPLANTATION

  •  

NASA’S CONCLUSIONS:

“The up-regulation of these genes is in no manner marginal (1.7-8.4 logs) with gene sites for collagen production and growth the most actively stimulated.”

“We have clearly demonstrated the bioelectric/biochemical potentiation of nerve stimulation and restoration in humans as a documented reality.”

“The most effective electromagnetic field for repair of trauma was square wave with a rapid rate of change (dB/dt) which saw cell growth increased up to 4.0 times.”

*NASA’s study is the first to clarify technologies and efficacy parameters for tissue growth and restoration.

 

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